CovidV1, Main, Exploration, bibRecord, 001687

Antibody against viruses in maternal and cord sera: specific antibody is concentrated on the fetal side of the circulation

Identifieur interne : 001687 ( Main/Exploration ); précédent : 001686; suivant : 001688

Antibody against viruses in maternal and cord sera: specific antibody is concentrated on the fetal side of the circulation

Auteurs : P. D. Griffiths ; S. I. Berney ; S. Argent ; R. B. Heath

Source :

Journal of Hygiene [ 0022-1724 ] ; 1982-10.

RBID : ISTEX:E50189B7E8121C0C8BC2A867EDAA92650C490902

Abstract

Paired maternal and cord sera from 100 pregnancies were tested for antibodies against herpes simplex virus, measles virus and respiratory syncytial virus by complement fixation and for antibodies against rubella virus, influenza A virus and influenza B virus by haemagglutination-inhibition. For four viruses (herpes simplex, measles, respiratory syncytial and rubella) higher levels of antibody were found in cord than in maternal sera. There was no difference between maternal and cord serum titres against influenza B virus but significantly higher levels of antibody against influenza A virus were found in maternal sera than in cord sera. This discrepancy was investigated by measuring antibodies against the surface antigens of influenza A by a complement fixation technique, and by single radial haemolysis. Both methods showed a preponderance of virus-specific antibody in cord sera. We conclude that IgG antibodies against most, if not all, viruses are concentrated on the fetal side of the circulation, but that conventional haemagglutination-inhibition techniques may fail to detect this difference.

Url:

DOI: 10.1017/S0022172400070832

Affiliations:

Le document en format XML

<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title>Antibody against viruses in maternal and cord sera: specific antibody is concentrated on the fetal side of the circulation</title>
<author><name sortKey="Griffiths, P D" sort="Griffiths, P D" uniqKey="Griffiths P" first="P. D." last="Griffiths">P. D. Griffiths</name>
</author>
<author><name sortKey="Berney, S I" sort="Berney, S I" uniqKey="Berney S" first="S. I." last="Berney">S. I. Berney</name>
</author>
<author><name sortKey="Argent, S" sort="Argent, S" uniqKey="Argent S" first="S." last="Argent">S. Argent</name>
</author>
<author><name sortKey="Heath, R B" sort="Heath, R B" uniqKey="Heath R" first="R. B." last="Heath">R. B. Heath</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">ISTEX</idno>
<idno type="RBID">ISTEX:E50189B7E8121C0C8BC2A867EDAA92650C490902</idno>
<date when="1982" year="1982">1982</date>
<idno type="doi">10.1017/S0022172400070832</idno>
<idno type="url">https://api.istex.fr/ark:/67375/6GQ-P09CT8JH-M/fulltext.pdf</idno>
<idno type="wicri:Area/Istex/Corpus">000120</idno>
<idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">000120</idno>
<idno type="wicri:Area/Istex/Curation">000100</idno>
<idno type="wicri:Area/Istex/Checkpoint">000803</idno>
<idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">000803</idno>
<idno type="wicri:doubleKey">0022-1724:1982:Griffiths P:antibody:against:viruses</idno>
<idno type="wicri:Area/Main/Merge">001716</idno>
<idno type="wicri:source">PMC</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2134211</idno>
<idno type="RBID">PMC:2134211</idno>
<idno type="wicri:Area/Pmc/Corpus">000237</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000237</idno>
<idno type="wicri:Area/Pmc/Curation">000237</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000237</idno>
<idno type="wicri:Area/Pmc/Checkpoint">000790</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000790</idno>
<idno type="wicri:Area/Ncbi/Merge">000E59</idno>
<idno type="wicri:Area/Ncbi/Curation">000E59</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">000E59</idno>
<idno type="wicri:doubleKey">0022-1724:1982:Griffiths P:antibody:against:viruses</idno>
<idno type="wicri:Area/Main/Merge">001708</idno>
<idno type="wicri:Area/Main/Curation">001687</idno>
<idno type="wicri:Area/Main/Exploration">001687</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title level="a">Antibody against viruses in maternal and cord sera: specific antibody is concentrated on the fetal side of the circulation</title>
<author><name sortKey="Griffiths, P D" sort="Griffiths, P D" uniqKey="Griffiths P" first="P. D." last="Griffiths">P. D. Griffiths</name>
<affiliation><wicri:noCountry code="subField">7BE</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Berney, S I" sort="Berney, S I" uniqKey="Berney S" first="S. I." last="Berney">S. I. Berney</name>
<affiliation><wicri:noCountry code="subField">7BE</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Argent, S" sort="Argent, S" uniqKey="Argent S" first="S." last="Argent">S. Argent</name>
<affiliation><wicri:noCountry code="subField">7BE</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Heath, R B" sort="Heath, R B" uniqKey="Heath R" first="R. B." last="Heath">R. B. Heath</name>
<affiliation><wicri:noCountry code="subField">7BE</wicri:noCountry>
</affiliation>
</author>
</analytic>
<monogr></monogr>
<series><title level="j">Journal of Hygiene</title>
<title level="j" type="abbrev">J. Hyg.</title>
<idno type="ISSN">0022-1724</idno>
<imprint><publisher>Cambridge University Press</publisher>
<pubPlace>Cambridge, UK</pubPlace>
<date type="published" when="1982-10">1982-10</date>
<biblScope unit="volume">89</biblScope>
<biblScope unit="issue">2</biblScope>
<biblScope unit="page" from="303">303</biblScope>
<biblScope unit="page" to="310">310</biblScope>
</imprint>
<idno type="ISSN">0022-1724</idno>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt><idno type="ISSN">0022-1724</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass></textClass>
<langUsage><language ident="en">en</language>
</langUsage>
</profileDesc>
</teiHeader>
<front><div type="abstract">Paired maternal and cord sera from 100 pregnancies were tested for antibodies against herpes simplex virus, measles virus and respiratory syncytial virus by complement fixation and for antibodies against rubella virus, influenza A virus and influenza B virus by haemagglutination-inhibition. For four viruses (herpes simplex, measles, respiratory syncytial and rubella) higher levels of antibody were found in cord than in maternal sera. There was no difference between maternal and cord serum titres against influenza B virus but significantly higher levels of antibody against influenza A virus were found in maternal sera than in cord sera. This discrepancy was investigated by measuring antibodies against the surface antigens of influenza A by a complement fixation technique, and by single radial haemolysis. Both methods showed a preponderance of virus-specific antibody in cord sera. We conclude that IgG antibodies against most, if not all, viruses are concentrated on the fetal side of the circulation, but that conventional haemagglutination-inhibition techniques may fail to detect this difference.</div>
</front>
</TEI>
<affiliations><list></list>
<tree><noCountry><name sortKey="Argent, S" sort="Argent, S" uniqKey="Argent S" first="S." last="Argent">S. Argent</name>
<name sortKey="Berney, S I" sort="Berney, S I" uniqKey="Berney S" first="S. I." last="Berney">S. I. Berney</name>
<name sortKey="Griffiths, P D" sort="Griffiths, P D" uniqKey="Griffiths P" first="P. D." last="Griffiths">P. D. Griffiths</name>
<name sortKey="Heath, R B" sort="Heath, R B" uniqKey="Heath R" first="R. B." last="Heath">R. B. Heath</name>
</noCountry>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/CovidV1/Data/Main/Exploration

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001687 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 001687 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Wicri/Sante
   |area=    CovidV1
   |flux=    Main
   |étape=   Exploration
   |type=    RBID
   |clé=     ISTEX:E50189B7E8121C0C8BC2A867EDAA92650C490902
   |texte=   Antibody against viruses in maternal and cord sera: specific antibody is concentrated on the fetal side of the circulation
}}

This area was generated with Dilib version V0.6.33.
Data generation: Fri Mar 27 18:14:15 2020. Site generation: Sun Jan 31 15:15:08 2021

Serveur d'exploration Covid

Antibody against viruses in maternal and cord sera: specific antibody is concentrated on the fetal side of the circulation

Antibody against viruses in maternal and cord sera: specific antibody is concentrated on the fetal side of the circulation

Source :

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

	Serveur d'exploration Covid
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.